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Mental and Behavioural Disorders Due to Multiple Drug Use (F19)

DSM-5-TR: Other (or Unknown) Substance Use Disorder

ICD-10-AM and DSM-5-TR may classify conditions differently. Refer to APA and WHO for complete diagnostic criteria.

Key Facts

  • ICD-10 RangeF10-F19
  • Subcodes5 subcodes
  • Australian PrevalencePolysubstance use is common among Australian drug users presenting to treatment services. Methamphetamine combined with cannabis is the most frequent polysubstance pattern.
  • Global PrevalencePolysubstance use is increasingly common worldwide, particularly combinations involving alcohol, cannabis, and stimulants.
  • Duration RequirementAs per individual substance categories (F10-F18)

Overview

This category is used when the substance use involves two or more psychoactive substances and it is not possible to determine which substance is most responsible for the disorder. This includes disorders arising from chaotic drug use or when substances from other categories (F11–F18) are mixed.

Diagnostic Criteria (ICD-10)

Core Features

  • Use of two or more psychoactive substances
  • Not possible to determine which substance is primarily responsible
  • Pattern of chaotic or indiscriminate drug use
  • Clinical features may include any combination of intoxication, dependence, withdrawal, or psychosis

Duration As per individual substance categories (F10-F18)

Exclusion Criteria

  • Disorder attributable to a single identified substance (use F10-F18)

ICD-10-AM Subcodes

CodeNameDescription
F19.0Acute intoxicationIntoxication due to multiple substances.
F19.1Harmful useHarmful use of multiple substances.
F19.2Dependence syndromeDependence on multiple substances.
F19.3Withdrawal stateWithdrawal from multiple substances.
F19.5Psychotic disorderPsychotic symptoms arising from multiple substance use.

Classification Boundaries

Includes

  • Multiple drug use NOS
  • Multiple drug abuse

Australian Clinical Context

Polysubstance use is common among Australian drug users presenting to treatment services. The AIHW National Drug Strategy Household Survey monitors patterns. Treatment often involves integrated care addressing multiple substance dependencies simultaneously.

Medicare (MBS) Pathways

Better Access to Mental Health Care
The primary Medicare pathway for mental health treatment in Australia. Requires a GP Mental Health Treatment Plan (MHTP) referral. Available for any clinically diagnosed mental disorder.

10 individual + 10 group sessions per calendar year

Provider TypeMBS ItemsSession Type
Clinical Psychologist80000–80025Psychological therapy (higher rebate)
Registered Psychologist80100–80123Focused psychological strategies
Occupational Therapist80125–80145Focused psychological strategies
Social Worker80150–80175Focused psychological strategies
Psychiatrist291, 296–299, 300–308Psychiatric consultation

GP referral items: 2700, 2701, 2715, 2717

Eligibility: Any clinically diagnosed mental disorder as defined by WHO ICD-10 Chapter V. Requires a GP or psychiatrist referral.

Exclusions:

  • Intellectual disability (use Complex Neurodevelopmental Disorder pathway or specialist referral)
  • Dementia and organic mental disorders (use specialist referral pathway)
  • Tobacco use disorder

State and territory drug and alcohol services may also apply alongside MBS. Complex presentations may require specialist coordination.

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Reference information sourced from MBS Online (mbsonline.gov.au). Item availability, rebates, and eligibility criteria may change. This is not billing advice — always verify current items before claiming. Last verified: April 2026.

Clinical Documentation Notes

When coding polysubstance use, if a primary substance can be identified, code under the specific substance category (F10–F18). F19 should only be used when the pattern is genuinely mixed and no single substance predominates. Document all substances used, including quantities and routes of administration.

Related Assessment Tools

Other validated instruments commonly used alongside the Mental and Behavioural Disorders Due to Multiple Drug Use (F19).

Related Diagnostic Codes

ICD-10-AM diagnostic codes commonly associated with the Mental and Behavioural Disorders Due to Multiple Drug Use (F19).

Frequently Asked Questions

When should I use F19 vs multiple specific substance codes?

Use F19 when the disorder genuinely arises from the combined use of multiple substances and no single substance predominates. If specific substances can be identified and their individual effects characterised, code each separately (e.g., F10.2 for alcohol dependence + F11.2 for opioid dependence).

References

  1. World Health Organization. ICD-10-AM.
  2. AIHW. National Drug Strategy Household Survey.
  3. American Psychiatric Association. DSM-5-TR. 2022.
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